Ana Alice Silva de Melo Gisane Cavalcante Fernandes 1 Felizane Mendes and Silva Jeanne Kelly Birth Souza Maria Lindinalva Ninos Bastos Maria Teresa Teixeira Xavier Would carry It to Introduction of numbers 2616/98 of the Health department defines as hospital Infection that one acquired during the internment or after the high one of the patient, since whom she has relation with the internment or some related procedure, and also that one that if presents 72h of internment after. To if analyzing some aspect in set she obtained to characterize the hospital infection. The clinical signals are basic in the daily evaluation of the 1 Graduandos in Nursing – College San Francisco de Barreiras – FASB. interned customers, mainly if these are in treatment of some infectious illness and antimicrobials use. The interest to search and to study on the infections hospital was born with the sprouting of the industries in the age of the government of Kubitschek, where, one occurred occasions of Staphylococcus Aureus. Causing in health professionals the interest to study and to search on the contamination of the environment, the care with the garbage and the reduction of the contamination of air. (MS, 2000). The first course of university level was created in the decade of 70, for the professionals of the National Institute of Social Providence, who were worried about the hospital infections. In this same time, the Hospital of Ipanema instituted 1 Commission of Control of Hospital, composed Infection for a surgeon, a physician, a bacteriologist, a nurse and a epidemiologista, with the intention to better know its indices of hospital infection and to install efficient strategies for its control (COAST, 1995). The infection in the neonatal period consists in one of the great concerns of pediatra, for being recognized difficult pathology of and being proven, to be simultaneously serious and to present mortality indices.